Erythema nodosum - I-Erythema Nodosum
☆ Kwiziphumo zika-2022 ze-Stiftung Warentest ezivela eJamani, ukwaneliseka kwabathengi ngeModelDerm bekungaphantsi kancinci kunokubonisana nge-telemedicine ehlawulweyo.
Ibonakala njengeqhuqhuva le-erythematous elibuhlungu emlenzeni.
References
Erythema nodosum lolona hlobo luqhelekileyo lwe-panniculitis, olubonakaliswa ngamaqhuqhuva abomvu abuhlungu, afumaneka ikakhulu kwimilenze engezantsi. Esona sizathu saso asikaziwa, kodwa kubonakala ngathi sisiphumo sempendulo ebaxiweyo kwizinto ezibangela ukuba zibangele. Nangona imvelaphi yayo ihlala ingaqinisekanga, kubalulekile ukulawula ezinye iimeko ezingaphantsi phambi kokuxilongwa primary erythema nodosum. Ingabonisa ukuqala kwezifo zesistim ezifana nosulelo, ukuvuvukala, umhlaza, okanye ukuphendula kumayeza. Izichukumisi eziqhelekileyo ziquka strep infections, tuberculosis, sarcoidosis, Behçet's disease, inflammatory bowel disease, certain medications, pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis ibhekisa kwiintlobo ezahlukeneyo zeemeko zokudumba ezichaphazela izicubu ezinamafutha phantsi kwesikhumba. Ezi meko aziqhelekanga ebantwaneni. Panniculitis inokuba ngumba ophambili kwimeko yenkqubo okanye ukusabela okwesibini kwizinto ezifana nosulelo, ukwenzakala, okanye amayeza athile. Kungakhathaliseki ukuba yintoni unobangela, uninzi lweentlobo ze- panniculitis zibonisa iimpawu ezifanayo, kuquka iintlungu ezibuhlungu, amaqhuqhuva abomvu phantsi kwesikhumba.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , ukudumba komgangatho wamafutha phantsi kwesikhumba, yimeko enqabileyo edla ngokubonakala njengamaqhuqhuva adumbileyo okanye amabala. Erythema nodosum (EN) lolona didi luxhaphakileyo, olusoloko lusenziwa zizinto ezahlukeneyo. Ngelixa malunga neepesenti ezingama-55 zamatyala azinasizathu esicacileyo, izinto ezibangela ukuba zibandakanye ukusuleleka, amayeza, izifo ezithile ezifana ne-sarcoidosis kunye nesifo samathumbu, ukukhulelwa kunye nomhlaza. I-EN idla ngokuvela kulutsha nakubantu abadala, ngokufuthi kwabasetyhini. Ihlala yandulelwa yimvakalelo eqhelekileyo yokugula ethatha iveki enye ukuya kwezintathu, eneempawu ezinjengomkhuhlane kunye nemiba ephezulu yokuphefumla. Emva koko, amaqhuqhuva abomvu avela, ngokuqhelekileyo emacaleni angaphandle eengalo nemilenze, ebangela intlungu. Esona sizathu se-EN asiqondwa ngokupheleleyo, kodwa kukholelwa ukuba ibandakanya i-immune complexes kwimithambo yegazi encinci ye-fat layer, ekhokelela ekudumbeni. Ngokuqhelekileyo, i-biopsy ibonisa ukuvuvukala kwi-fat layer ngaphandle komonakalo kwimithambo yegazi. Nangaphandle konyango oluthile lwesizathu esisisiseko, i-EN ihlala izisombulula ngokwayo. Ke, uninzi lwezigulana zifuna kuphela ukhathalelo lwenkxaso kwiimpawu zabo.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
I-Erythema nodosum ifunyaniswa ngonyango. I-biopsy inokuthatyathwa kwaye ihlolwe nge-microscope ukuqinisekisa ukuxilongwa okungaqinisekanga. I-X-ray yesifuba kufuneka yenziwe ukulawula izifo ze-pulmonary, ngokukodwa i-sarcoidosis kunye nesifo sofuba.